Phytofabrication of biocompatible zinc oxide nanoparticle using Gymnema sylvestre and its potent in vitro antibacterial, antibiofilm, and cytotoxicity against human breast cancer cells (MDA-MB-231).

The increasing incidence of breast cancer and bacterial biofilm in medical devices significantly heightens global mortality and morbidity, challenging synthetic drugs. Consequently, greener-synthesized nanomaterials have emerged as a versatile alternative for various biomedical applications, offering new therapeutic avenues. This study explores the synthesis of biocompatible zinc oxide (ZnONPs) nanoparticles using Gymnema sylvestre and its antibacterial, antibiofilm, and cytotoxic properties.

Molecular structure, spectroscopic (FT-IR, FT-Raman), NBO analysis of N,N'-diphenyl-6-piperidin-1-yl-[1,3,5]-triazine-2,4-diamine.

In the present work, we have synthesized and reported a combined experimental and theoretical study on the molecular structure, vibrational spectra and HOMO-LUMO analysis of N,N'-diphenyl-6-piperidin-1-yl-[1,3,5]-triazine-2,4-diamine (C20N6H22). The FT-IR and FT-Raman spectra of N,N'-diphenyl-6-piperidin-1-yl-[1,3,5]-triazine-2,4-diamine were recorded. The molecular geometry, harmonic vibrational wavenumbers and bonding features of the title molecule in the ground-state have been calculated by using the density functional B3LYP method with 6-31G(d) as basis set.

2,4-Dichloro-N-phenethyl-benzene-sulfonamide.

In the title compound, C(14)H(13)Cl(2)NO(2)S, the dihedral angle between the phenyl ring and the benzene ring is 69.94 (9)°. Two short intra-molecular C-H⋯O contacts occur and a weak inter-molecular C-H⋯π inter-action is seen in the crystal.

4-Amino-phenyl naphthalene-1-sulfonate.

In the title compound, C(16)H(13)NO(3)S, the plane of the amino-benzene ring makes a dihedral angle of 61.04 (6)° with the naphthalene ring system. Both ring systems form weak intra-molecular C-H⋯O hydrogen bonds with the sulfonate group.