IL-35 may prevent the exacerbation of aspiration pneumonia involving Porphyromonas gingivalis by suppressing IL-17 production.

Periodontitis was reported to be associated with aspiration pneumonia. However, the relationship between periodontitis and aspiration pneumonia remains unclear. This study investigated the virulence factor of Porphyromonas gingivalis, which exacerbates aspiration pneumonia, and the role of IL-35, an inhibitory heterodimeric cytokine of EBI3 and p35, in aspiration pneumonia using Ebi3 knockout (KO) mice.

Investigating the Influence of Limb Blood Flow on Contraction-Induced Muscle Growth and the Impact of that Growth on Changes in Maximal Strength.

Abstract: Changes in skeletal muscle size may be affected by resting blood flow (e.g., nutrient delivery) and this change in size is a hypothesized mechanism for changes in strength.

Does Unilateral High-Load Resistance Training Influence Strength Change in the Contralateral Arm Also Undergoing High-Load Training?

Training one limb with a high-load has been shown to augment strength changes in the opposite limb training with a low-load (via cross-education of strength), indicating that within-subject models can be problematic when investigating strength changes. This study examined if the cross-education of strength from unilateral high-load training could augment the strength changes in the opposite arm undergoing the same unilateral high-load training. 160 participants were randomized to one of four groups: (1) training on the dominant arm followed by the non-dominant arm (D + ND), (2) training on the dominant arm only (D-Only), (3) training on the non-dominant arm only (ND-Only), and (4) a non-exercise control.

The Effect of Isometric Handgrip Training With and Without Blood Flow Restriction on Changes in Resting Blood Pressure.

To investigate the effects of high-intensity contractions and low-intensity contractions with and without blood flow restriction on changes in blood pressure and hemodynamic parameters. A total of 179 participants (18-35 years) were randomly assigned to one of three training groups that exercised 3 times per week for six weeks or a non-exercise control group. The groups are as follows: 1) Control [CON,  = 44]; 2) completed 4 sets of two-minute isometric contractions at 30% maximal voluntary contraction [LI,  = 47]; 3) completed 4 sets of two-minute isometric contractions at 30% maximal voluntary contraction with a 12 cm cuff inflated to 50% of arterial occlusion pressure [LI+BFR,  = 41]; or 4) completed 4 maximal isometric contractions lasting 5 seconds [MAX,  = 47].