Tracheal bronchogenic cyst: a rare cause of stridor.

A 6-month-old child with stridor from 3 months of age presented with interim worsening following a respiratory infection. Airway evaluation revealed a smooth, polypoidal mass herniating in and out of the airway with each respiratory cycle, from the anterior surface of the upper trachea. Computerized tomography showed a non-enhancing cystic mass in anterior neck protruding into the upper trachea through an anterior tracheal defect.

Investigation of magnesium aluminometasilicate (Neusilin US2) based surface solid dispersion of sorafenib tosylate using QbD approach: and pharmacokinetic study.

Background And Purpose: Sorafenib tosylate (SFN), a potent multikinase inhibitor, is used for the treatment of various cancers. However, it shows limited therapeutic applications due to its poor biopharmaceutical properties. The aim of the present investigation is to develop surface solid dispersion (SSD) of SFN using adsorbent to improve its solubility, bioavailability and therapeutic efficacy.

Clinical Insights Into Lower Incisor Extraction for Orthodontic Treatment: A Case Report.

Extracting a single lower front tooth can be an appropriate treatment for class I malocclusions when the alignment of the upper teeth is normal and there is an adequate overlap of the teeth. This approach is particularly effective in cases of significant crowding in the lower front teeth, especially when the space deficiency exceeds 4-5 mm and the combined width of the lower front teeth surpasses 83 mm. It is also a viable option for malocclusions resulting from discrepancies in tooth size, such as narrower upper front teeth or larger lower front teeth.

Management implications of latent TB among under-five children at risk: Insights from a community study in Mumbai, India.

Background: Latent tuberculosis infection (LTBI) management is crucial to WHO's End TB Strategy. Indian guidelines recommend treating under-five children with household TB contacts after ruling out active TB, regardless of TBI testing. However, the precise LTBI burden among children in high TB burden settings like India is unknown.

Presurgical Nasoalveolar Molding and Columella Lengthening for Early Unilateral Cleft Lip and Palate Rehabilitation: A Comprehensive Clinical Case Report.

Aim And Background: In presurgical infant orthopedics, nasoalveolar molding (NAM) therapy has gained more popularity worldwide in treating patients with cleft lip and palate because of its soft tissue nasal corrections in addition to the alignment and close approximation of the cleft alveolar segments, which gives better postsurgical stability and esthetics with minimal tissue tension and scar formation to the patients.The clinical case report aims to show the better post-NAM results, which had helped to gain better postsurgical results in terms of stability and aesthetics in hard and soft tissues.

Case Description: This clinical report presents the case of a 9-day-old female patient reported in the Department of Orthodontics and Dentofacial Orthopedics at Sharad Pawar Dental College and Hospital with nonsyndromic complete left-sided unilateral cleft lip and palate with a defect size of 13 mm, which was treated with a presurgical nasoalveolar molding (PNAM) appliance.