Publications by authors named "R Kalmann"
The following case potentially provides insight into the mechanisms of lymphogenic metastasis in sinonasal cancer. A 63-year-old patient who presented with progressive diplopia and left-sided periocular pain was diagnosed with a cT4bN0M0 mucosal melanoma of the ethmoid sinus. She underwent a combined endonasal and transcranial tumor resection, and an orbital exenteration.
View Article and Find Full Text PDFArticle Synopsis
- The conjunctival epithelium has two key cell types: goblet cells that produce mucus and keratinocytes that secrete water, with keratinocytes presenting mucins on their surface.
- Research involves long-term organoid cultures of human and mouse conjunctiva, revealing essential gene expression and identification of conjunctival stem cells.
- The study also explores viral infections (HSV1, hAdV8, SARS-CoV-2) in conjunctival cultures, demonstrating treatment options for some infections and documenting gene expression changes induced by these viruses, highlighting the potential for organoid transplantation to study conjunctival health and disease.
Orbital Inflammation and Dacryoadenitis after COVID-19 Vaccination.
Case Rep Ophthalmol
October 2022
The aim of this paper was to report the case of a patient with orbital inflammation and dacryoadenitis after COVID-19 vaccination. During the COVID-19 pandemic, we noticed an increase of post-viral syndromes, both linked to infection and to vaccination. A 53-year-old male presented with proptosis, chemosis, hypotropia, and ophthalmoplegia of the right eye, 1 day after his COVID-19 booster shot.
View Article and Find Full Text PDFPurpose: Graves' orbitopathy (GO) is a rare condition in children often considered to be a less severe condition than at an older age. The aim of our study was to analyse if there are any factors that distinguish paediatric from adult GO in order to provide guidelines for assessing and managing paediatric GO.
Methods: Study design is a multicentre retrospective observational case series; 115 paediatric patients diagnosed with GO who visited our university medical centres in the Netherlands and Iran between 2003 and 2019 were submitted for complete ophthalmological examinations, serological testing and/or orbital imaging.