Publications by authors named "R Kalaitzidis"
Kidney disease is a public health epidemic affecting 10% of the population worldwide with a constantly rising incidence, and it is an important contributor to morbidity and mortality. Type 2 diabetes mellitus (T2DM) is a chronic complex condition with a rising incidence worldwide. T2DM remains the principal cause of chronic kidney disease (CKD), which is related to a high risk for cardiovascular (CV) events, end-stage kidney disease (ESKD), and, overall, considerable morbidity and mortality.
View Article and Find Full Text PDFArticle Synopsis
- - SGLT2 inhibitors not only help with blood sugar, heart health, and kidney protection but also influence blood pressure, body weight, and fat metabolism.
- - Blood pressure decreases can vary based on individual health history, with modest drops in body weight (1-2 kg) mainly due to fat loss from excess sugar and calorie loss.
- - Changes in lipid levels include slight reductions in triglycerides and increases in both HDL and LDL cholesterol, but the exact reasons behind these effects are still being researched.
Background: Cardio-renal syndrome, characterized by simultaneous cardiac and renal impairment, presents significant challenges in patient prognostication and management. This study aimed to investigate the C-reactive protein-to-albumin ratio (CRP/Albumin ratio) as a prognostic marker in patients with cardiorenal syndrome.
Methods: This observational cohort study included consecutive patients hospitalized for cardiorenal syndrome.
Cognitive impairment and subsequent dementia are considered significant health challenges. In patients with established dementia, it is argued that hypertension is the main risk factor for small vessel ischemic disease and additional cortical white matter lesions. Cognitive domains and impairments associated with hypertension include learning, memory, attention, abstract reasoning, mental flexibility, psychomotor skills, and executive function.
View Article and Find Full Text PDFBackground: Flavonoids, the main class of polyphenols, exhibit antioxidant and antihypertensive properties.
Aim: To prospectively investigate the impact of flavonoids on arterial stiffness in patients with chronic kidney disease (CKD) stages I-IV.
Methods: In this prospective, single-arm study, CKD patients with arterial hypertension and diabetes mellitus were enrolled.