Publications by authors named "R Kaku"
Obstructive sleep apnea (OSA), a highly prevalent and serious disorder with significant complications, causes considerable daytime and nighttime symptoms as well as long-term consequences and is yet an underdiagnosed and inadequately treated condition. Patients with OSA undergo frequent awakenings during the sleep cycle and find it impossible to get restorative sleep. Individuals are extremely fatigued, sleepy, and irritable throughout the day.
View Article and Find Full Text PDFMeasuring pain objectively or quantitatively is difficult. Since urine oxytocin (OXT) concentration has been reported to be potentially associated with chronic pain. We conducted a pilot study to evaluate the relationship between changes in numerical rating scale (NRS) score following nerve block and urine OXT concentration in patients with chronic pain.
View Article and Find Full Text PDFA man in his 50s was diagnosed with right upper lobe non-small-cell lung cancer (cT3N1M0, stage ⅢA) on bronchoscopy. The tumor was located at the right hilum and was bordered extensively on the pulmonary artery. We observed significant tumor shrinkage (ycT1bN1M0, stage ⅡB), following three cycles of systemic chemotherapy combined with an immune checkpoint inhibitor and performed right upper sleeve lobectomy + ND2a-2 via thoracotomy for radical resection.
View Article and Find Full Text PDFArticle Synopsis
- Effective communication is vital in ICUs for both patient care and the well-being of healthcare professionals (HCPs), with distributed leadership potentially enhancing teamwork and communication.
- A social network analysis was conducted using wearable sensors to gauge face-to-face interactions among ICU staff, while also evaluating HCPs' well-being using the CES-D questionnaire.
- The study revealed that the implementation of a distributed leadership structure in 2017 and 2018 resulted in a significant increase in the number of nurses capable of leading tasks compared to a traditional leadership model in 2016.
Myostatin expression in lung cancer induces sarcopenia and promotes cancer progression.
Gen Thorac Cardiovasc Surg
April 2024
Objectives: Many studies have demonstrated that sarcopenia among lung cancer predicts poor prognosis due to cancer progression. However, the cytokines that link sarcopenia and lung cancer progression remain unidentified. This study aimed to investigate whether lung cancer producing myostatin, which induces skeletal muscle atrophy, leads to sarcopenia and promotes cancer progression in patients with resected lung cancer.
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