[Changes in plasma volume and electrolytes after treatment of therapy-resistant hypertension with diazoxide and furosemide].

10 patients (5 females, 5 males, average age 50.2 +/- 5.8 years) with a therapy-resistant hypertension were for 10 days treated with injections of diazoxide and furosemide (hypertonalum and furesis).

[Results of long-term therapy in hypertension].

Two groups of patients with hypertension ( n = 16 and 20) with comparable average age and degree of severity of clinical hypertension were controlled in an ambulatory long-term investigation for 18 months. While one group was treated with an antihypertensive standard therapy, the other group got a fixed combination of dihydralazin and propranolol. In both groups a significant decrease of the systolic and diastolic initial blood pressure was seen, which was more pronounced in the second group.