Background: The inter-pregnancy interval (IPI) refers to the time between one pregnancy and the next. Studies have shown that IPIs shorter than 18 months are linked to negative outcomes, such as preterm delivery, infant mortality, and small-for-gestational-age birth. The aim of this study was to measure the prevalence and risk factors of short inter-pregnancy intervals among women receiving care at primary health centers in Jeddah, Saudi Arabia.
View Article and Find Full Text PDFSubdermal contraceptive implants are among the most effective and reversible contraceptive methods available today. Implanon®️, approved by the US FDA, is widely used for long-term family planning due to its extended contraceptive effects. Although generally safe, these implants can occasionally lead to rare but serious complications, such as migration into deeper axillary structures.
View Article and Find Full Text PDFIntegration of multiple data sources presents a challenge for accurate prediction of molecular patho-phenotypic features in automated analysis of data from human model systems. Here, we applied a machine learning-based data integration to distinguish patho-phenotypic features at the subcellular level for dilated cardiomyopathy (DCM). We employed a human induced pluripotent stem cell-derived cardiomyocyte (iPSC-CM) model of a DCM mutation in the sarcomere protein troponin T (TnT), TnT-R141W, compared to isogenic healthy (WT) control iPSC-CMs.
View Article and Find Full Text PDFMedicinal plant-based cerium oxide nanoparticles (CeONPs) possessed excellent antimicrobial properties against multiple strains of Gram-positive and Gram-negative bacteria. The CeONPs are popular because their electropositive charged surface causes oxidation of plasma membrane and facilitates the penetration of CeONPs inside the pathogen body. In the present research work, CeONPs stabilized with Mentha leaf extract; as a result, nanoparticles surface-bonded with various functional groups of phytochemicals which enhanced the therapeutic potential of CeONPs.
View Article and Find Full Text PDFBackground: 2020 Coronavirus disease 2019 (COVID-19) has become a global health crisis, so hand alcohol-based sanitizers have become essential to preventive measures. Previous studies reported that hand sanitizers could kill bacteria and viruses; however, using them excessively can lead to health problems if misused. In light of sanitizer overuse, the availability of various products and qualities in the market, and the absence of data on skin problems, we conducted a survey study about the impact of commonly used sanitizers on skin health, particularly on hands.
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