Publications by authors named "R K Topno"
Prevalence of Japanese encephalitis infection in children below 15 years' age, Bihar.
Diagn Microbiol Infect Dis
February 2025
Article Synopsis
- Japanese encephalitis (JE) is a major cause of acute encephalitis syndromes, with Bihar being the third highest in reported cases in India, after Uttar Pradesh and Assam.
- A recent study in Bihar, particularly in districts like Patna, Muzaffarpur, and Gaya, found that JE virus (JEV) is a key contributor to AES cases, with a detection rate of 8.79% in analyzed samples.
- The study indicated a demographic trend where most affected patients are children aged 6-10 years, and there's a need for increased awareness and preventive measures despite a decrease in the case fatality rate.
Article Synopsis
- - Postpartum pubic symphysis diastasis is a rare condition often linked to complications during childbirth, such as difficult labor or larger babies.
- - While most cases are managed conservatively, surgery may be necessary for severe diastasis (over 4 cm) to prevent long-term issues like chronic pain and functional disabilities.
- - A study involving four women (ages 20-30) with over 7 cm of diastasis demonstrated successful outcomes with surgical intervention, allowing for early ambulation and full recovery within three months.
Article Synopsis
- Post-kala-azar dermal leishmaniasis (PKDL) is a skin condition affecting some individuals who have recovered from visceral leishmaniasis (VL), and it plays a role in the spread of VL.
- The rK39 rapid test is not effective for diagnosing PKDL due to lingering antileishmanial antibodies from past VL infections.
- The CL Detect™ Rapid Test showed 73.3% sensitivity and 100% specificity, making it a valuable tool for screening and monitoring PKDL in regions where the disease is common.
Article Synopsis
- A study was conducted to evaluate the treatment outcomes of single-dose liposomal amphotericin B for visceral leishmaniasis (VL) and post-kala-azar dermal leishmaniasis (PKDL), involving 527 cases, primarily VL.
- The cure rate for VL was found to be 95%, with significant differences in treatment success between genders and age groups; males had higher success rates than females, while younger patients (≤23 years) also fared better.
- The study highlighted that PKDL patients treated with this drug had a significantly shorter duration of disease development compared to those who received alternative treatments, emphasizing the need for ongoing monitoring of treatment strategies.
Hip joint is a ball and socket type of joint and its anatomic features makes it very stable. However, Incidence of hip dislocation has increased recently due to high energy trauma like road traffic accident, fall from height etc. It is usually associated with fracture of femoral head, neck, shaft and acetabular wall.
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