Root apoplastic barrier mechanism: an adaptive strategy to protect against salt stress.

From soil to plant, the water and ions, enter the root system through the symplast and apoplast pathways. The latter gains significance under salt stress and becomes a major port of entry of the dissolved salts particularly the sodium ions into the root vasculature. The casparian strip (CS), a lignified barrier circumambulating the root endodermal cells' radial and transverse walls regulates the movement of water and solutes in and out of the stele.

Designing multi-epitope vaccine against human cytomegalovirus integrating pan-genome and reverse vaccinology pipelines.

Human cytomegalovirus (HCMV) is accountable for high morbidity in neonates and immunosuppressed individuals. Due to the high genetic variability of HCMV, current prophylactic measures are insufficient. In this study, we employed a pan-genome and reverse vaccinology approach to screen the target for efficient vaccine candidates.

The Synthesis and Characterization of Selenium-Doped Bioglass.

Background Bioactive glass, which can form strong bonds with tissues, particularly bones, has become pivotal in tissue engineering. Incorporating biologically active ions like selenium enhances its properties for various biomedical applications, including bone repair and cancer treatment. Selenium's antioxidative properties and role in bone health make it a promising addition to biomaterial.

Integrating pan-genome and reverse vaccinology to design multi-epitope vaccine against Herpes simplex virus type-1.

Unlabelled: Herpes simplex virus type-1 (HSV-1), the etiological agent of sporadic encephalitis and recurring oral (sometimes genital) infections in humans, affects millions each year. The evolving viral genome reduces susceptibility to existing antivirals and, thus, necessitates new therapeutic strategies. Immunoinformatics strategies have shown promise in designing novel vaccine candidates in the absence of a clinically licensed vaccine to prevent HSV-1.