Shared intention and shared awareness for conditional automated driving: An online, randomized video experiment.

Objectives: In conditional automation for automated vehicles (AVs), drivers are tasked with remaining vigilant and ready to assume control should the system encounter a malfunction. However, little to no information is provided to the driver either about the AV's intended maneuvers or the AV's awareness of potential threats in the surrounding environment. To address this research gap, the present study proposes 2 human-machine interaction (HMI) concepts: Firstly, the shared intended pathway (SIP), which presents a forecast of the AV's intended maneuvers and, secondly, object recognition bounding boxes (ORBBs), which place transparent blue squares around other road users likely to contribute to a crash.

Engineered PVA-tamarind gum-based biocomposite for sustained ophthalmic delivery of moxifloxacin: Effect of nanocellulose on physicochemical, mechanoelectrical and permeation kinetics.

Widely used polysaccharide-based films in ophthalmic drug delivery have major limitations of inadequate mechanical strength, poor electrical conductivity, and insufficient ocular drug permeability. Moxifloxacin (MFX) biocomposite film of adequate mechanoelectrical properties was developed for sustained ophthalmic drug delivery. Nanocellulose (NC) incorporated (2.

Improved Dissolution Time and Oral Bioavailability of Pioglitazone Using Liquisolid Tablets: Formulation, Characterization, and Pharmacokinetics in Rabbits.

In the current study, it was intended to prepare liquisolid tablets of pioglitazone HCl to improve the bioavailability and dissolution time of the drug, as it has low solubility in water. Mathematical formulas were adopted, and the quantities of the carrier (MCC), coating material (colloidal silicon dioxides), and nonvolatile liquid vehicle (Tween 80) were taken. Various ratios of the drug to liquid and carrier to coating had been used in the formulation of liquisolid compacts.