Proteomic Analysis of Single Hairs.

Hair is a ubiquitous and robust mammalian tissue with biological, clinical, forensic, social, and economic significance. The hair shaft proteome reflects both structural proteins, dominated by cuticular intermediate filament keratins and associated proteins, and proteins involved in the final cellular processes of terminally differentiating corneocytes prior to cornification. These distinct biological processes involve cell maintenance, biosynthesis, senescence, and xenobiotic response.

Epigenetic modifications control CYP1A1 Inducibility in human and rat keratinocytes.

Serially passaged rat keratinocytes exhibit dramatically attenuated induction of Cyp1a1 by aryl hydrocarbon receptor ligands such as TCDD. However, the sensitivity to induction can be restored by protein synthesis inhibition. Previous work revealed that the functionality of the receptor was not affected by passaging.

Aging iridium oxide catalyst inks: a formulation strategy to enhance ink processability for polymer electrolyte membrane water electrolyzers.

Iridium oxide (IrO) is recognized as a state-of-art catalyst for anodes of low-temperature polymer-electrolyte membrane water electrolyzers (PEMWE), one of the promising clean energy technologies to produce hydrogen, a critical energy carrier for decarbonization. However, typical IrO ink formulations are challenging to process in liquid-film coating processes because of their poor stability against gravitational settling and low viscosities. Here we report on time evolution of the microstructure of concentrated IrO inks in a water-rich dispersion medium, probed using a combination of rheology and X-ray scattering for up to four days.