Probing the nature of intramolecular (sp)C-H⋯Cu(I) interactions in organo thione copper(I) cages.

The assessment of copper(I) and hydrogen interactions is challenging and should be approached with caution. In this paper, we report an assessment of multiple copper(I) and hydrogen interactions in two unique copper(I) thione cages. Copper(I) -heterocyclic thione cages [{Cu(-Br)(-L1)}] (1) and [{Cu(-I)(-L1)}] (2) were synthesized and characterized with proximity enforced Cu⋯H interactions.

A systematic review of portable technologies for the early assessment of motor development in infants.

Early screening and evaluation of infant motor development are crucial for detecting motor deficits and enabling timely interventions. Traditional clinical assessments are often subjective, without fully capturing infants' "real-world" behavior. This has sparked interest in portable, low-cost technologies to objectively and precisely measure infant motion at home, with a goal of enhancing ecological validity.

Navigating Fear: Women's Perceptions of Safety and Vulnerability in the Urban Landscape of Sambalpur, India.

Vulnerability is the perception of being exposed and susceptible to potential harm or adversity. This study underscores the critical role of individual women's perceived vulnerability in shaping their sense of safety and risk of victimization within the urban landscape. Focusing on women aged 15-49 years in Sambalpur city and its surrounding areas, the research draws on in-depth interviews and focus group discussions, analyzed through a phenomenological lens.

Synthesis, Characterization, and Antimicrobial Activity of Urea-Containing α/β Hybrid Peptides against and Methicillin-Resistant .

The insertion of β-amino acids and replacement of the amide bond with a urea bond in antimicrobial peptide sequences are promising approaches to enhance the antibacterial activity and improve proteolytic stability. Herein, we describe the synthesis, characterization, and antibacterial activity of short αβ cationic hybrid peptides LA-Orn-βAcc-PEA, ; LA-Lys-βAcc-PEA, ; and LA-Arg-βAcc-PEA, in which a C12 lipid chain is conjugated at the N terminus of peptide through urea bonds. Further, we evaluated all the peptides against both and methicillin-resistant (MRSA) and their multidrug resistant (MDR) clinical isolates.

Consensus Based Indian Guidelines for the Management of Pemphigus Vulgaris and Pemphigus Foliaceous.

Pemphigus is an autoimmune blistering disorder characterized by the presence of intraepidermal blisters and erosions, primarily affecting the mucosa and/or skin. There are no established Indian guidelines for the management of pemphigus, and Western guidelines cannot be directly applied due to differences in clinicodemographic profiles, comorbidities, and resource limitations. These guidelines aim to provide Indian dermatologists with evidence-based and consensus-driven recommendations for the management of pemphigus vulgaris (PV) and pemphigus foliaceous (PF), taking into account the unique challenges posed by the Indian healthcare setting.