Publications by authors named "R K Kochhar"
Article Synopsis
- Acute pancreatitis (AP) is a serious condition that can range from mild to severe, with complications like infections and organ failure becoming more common due to the increased presence of multi-drug-resistant organisms linked to improper antibiotic use.
- * The study aims to explore the experiences of patients with suspected infected pancreatic necrosis (IPN), focusing on identifying the prevalence of multi-drug-resistant organisms (MDROs) and understanding their antibiotic resistance.
- * Data was collected from 130 patients at a tertiary hospital in India, revealing that a majority had significant pancreatic necrosis, with high rates of organ failure and infections, particularly in the respiratory tract, and showing specific microbial resistance patterns.
Background: The standard salvage technique used for difficult bile duct cannulation is precut sphincterotomy, whereas endoscopic ultrasound-guided rendezvous technique (EUS-RV) is a relatively newer method. Prospective comparative data between these 2 techniques as salvage for biliary access in patients with benign biliary disease and difficult bile duct cannulation is lacking.
Objective: To compare EUS-RV and precut sphincterotomy as salvage technique for difficult bile duct cannulation in benign biliary obstruction.
Background: In patients with squamous cell carcinoma of the anus (SCCA), magnetic resonance (MR) imaging is recommended for pre-treatment staging prior to chemo-radiotherapy (CRT), but large-scale evaluation of its staging performance is lacking.
Methods: We re-characterised pre-treatment MRs from 228 patients with non-metastatic SCCA treated consecutively by CRT (2006-2015) at one UK cancer centre. We derived TN staging from tumour size (mrTr) and nodal involvement (mrN), and additionally characterised novel beyond TN features such as extramural vascular invasion (mrEMVI) and tumour signal heterogeneity (mrTSH).
Introduction: Low-grade appendiceal mucinous neoplasms (LAMNs) are classified as non-perforated (pTis, pT3) or perforated (pT4), and considered precursors of pseudomyxoma peritonei (PMP). This study aims to quantify the risk of developing PMP from pTis and pT3 LAMNs.
Materials And Methods: Retrospective analysis of a prospectively collected database identified LAMN patients referred to a specialist centre from 2004 to 2019.
Article Synopsis
- - A new machine learning tool was developed to predict the risk of post-ERCP pancreatitis (PEP) using data from 12 clinical trials, aiming to improve decision-making regarding patient care.
- - The tool was trained on 7389 patients, considering various risk factors and interventions, achieving a predictive accuracy (AUC) of 0.70 in the training phase and 0.74 in a pilot study with 135 patients.
- - This study shows that the model can effectively help identify patients at low risk for PEP, potentially reducing unnecessary post-procedural monitoring.