Publications by authors named "R K Katosova"

In experiments on mice the authors studied the correlation of the levels of the activity of a number of enzymes (dehydrogenase and acid phosphatase) of lymphocytes and neutrophils at three levels of organization: subcellular--inside the lymphocytes and neutrophils; intercellular--coordination of the enzymatic activity of two types of blood cells; temporary--inter-conjunction of the levels of metabolism in the blood cells prior to and in dynamics after infection. R. P.

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Succinic dehydrogenase (SDH) activity in peripheral blood lymphocytes has been studied in progressing experimental malaria on a P. yoelii model, the strain 265 BY; the multinipple rats Mastomys natalensis. Cytochemical method employing n-nitrotetrazolium violet was used.

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Clinical and immunological studies were performed in 45 patients with HCD. A group of patients was investigated by conventional immunology tests. spontaneous and active rosette formation, theophylline test, immunofluorescent B-lymphocyte investigation, IgA, IgM, IgG and circulating immune complexes (IC) levels measurement.

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The activity of succinate, lactate and alpha-glycerophosphate dehydrogenases, as well as acid phosphatase, in the lymphocytes and neutrophils of the blood was studied in noninbred white mice prior to the intraperitoneal injection of 1 LD50 of staphylococcal toxin. As the result of intoxication, a half of the animals died and the other half survived. The two groups of the animals differed in the levels of the activity of succinate dehydrogenase and hyaloplasmatic alpha-glycerophosphate dehydrogenase in the neutrophils and lymphocytes, and also differed in the stability of correlations between the activity of succinate and lactate dehydrogenases in the lymphocytes and neutrophils and, besides, between the activity of lactate dehydrogenase in these types of cells.

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Molecular mechanisms of metabolic modifications in blood cells were found to be associated with immunological tolerance to Coxsackie A virus in the modelling of chronic systemic diseases in rats. Blood cellular enzymatic activity correlated with morphological damage in internal organs. Cytochemical analysis is an informative test for investigating destructive and inflammatory changes in the affected organs.

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