Publications by authors named "R K Clifton"
Sex Differences in Long COVID.
JAMA Netw Open
January 2025
Importance: A substantial number of individuals worldwide experience long COVID, or post-COVID condition. Other postviral and autoimmune conditions have a female predominance, but whether the same is true for long COVID, especially within different subgroups, is uncertain.
Objective: To evaluate sex differences in the risk of developing long COVID among adults with SARS-CoV-2 infection.
Article Synopsis
- Gestational diabetes mellitus (GDM) is a common pregnancy complication, requiring glycaemic control to prevent negative outcomes for both the mother and baby, with about 25% needing medication like insulin or metformin.
- A study will compare the effectiveness and safety of metformin versus insulin in a diverse group of 1572 pregnant individuals needing treatment, tracking their health and their children's health for two years.
- Ethical approval has been obtained, and plans include publishing detailed results on the findings related to treatment experiences and safety outcomes.
Article Synopsis
- A study aimed to improve dairy herd reproduction through targeted management by predicting pregnancy risk in cows based on available farm data.
- Researchers analyzed data from 108 UK dairy herds, split into training (80%) and testing (20%) datasets, while categorizing cows by parity (nulliparous, primiparous, multiparous).
- An XGBoost model was developed to predict insemination outcomes, with moderate prediction accuracy (AUC scores around 0.59 to 0.63) but strong calibration, indicating that predicted and actual pregnancy risks were closely aligned.
Objective: To evaluate the risks of adverse maternal and neonatal outcomes associated with pregnancies complicated by hepatitis C virus (HCV) infection.
Methods: This is a secondary analysis of a multicenter prospective cohort study of HCV infection in pregnancy. Participants were screened for HCV infection with serum antibody tests, and each participant with a positive HCV result (case group) was matched with up to two individuals with negative HCV results (control group) prospectively by gestational age (±2 weeks) at enrollment.
Since 2004, the prevalence of lameness in sheep flocks in England has reduced as farmers have adopted evidence-based management practices to control lameness. In 2011, the Farm Animal Welfare Council proposed a target prevalence of <2% lameness in sheep by 2021. This study investigated whether that target had been achieved and determined which practices were associated with prevalence of lameness.
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