Publications by authors named "R K Chavda"
Hepatic arterial infusion therapy involves surgically implanting a subcutaneous hepatic arterial infusion pump with the catheter tip at the hepatic artery. This pump directly delivers chemotherapy to the liver, which may reduce systemic toxicity, improve resectability, and treat unresectable hepatic lesions. This therapy is used in primary or metastatic hepatic malignancies.
View Article and Find Full Text PDFAcne and sensitive skin can take a profound toll on patients' well-being, which can be exacerbated if the conditions are experienced together. This narrative review aims to identify appropriate treatments to facilitate a holistic management approach to acne (One Acne™), sensitive skin, and acne-induced sequelae and describe the role of treatments in improving skin quality. Topical retinoids are considered the preferred first-line option for acne treatment by dermatologists, either as monotherapy or in combination with other treatments, because of their ability to target various aspects of the disease.
View Article and Find Full Text PDFBackground: Artificial daylight photodynamic therapy (ADL-PDT) is an alternative, all-year applicable, nearly painless treatment approach for actinic keratoses (AK) with comparable effectiveness to daylight or conventional PDT. At the time this study was initiated, methyl aminolevulinate (MAL) was the only photosensitizer approved for ADL-PDT in Germany.
Objective: To gain comprehensive insights into the practicability of MAL-ADL-PDT in patients with AK using different artificial daylight sources under real-world conditions.
Article Synopsis
- The study investigated the effects of trifarotene, a medication with skin-lightening properties, on acne-induced hyperpigmentation (AIH) in patients aged 13-35 suffering from moderate acne vulgaris (AV), alongside a skincare regimen for a duration of 24 weeks.
- Results showed that trifarotene significantly improved overall disease severity (ODS) and hyperpigmentation reduction compared to a control vehicle, particularly noticeable by Week 24.
- Patients reported increased satisfaction with treatment adherence due to a skincare routine that minimized irritation, and trifarotene exhibited a better safety profile than the vehicle.
Article Synopsis
- Acne is a common skin condition that significantly affects the self-confidence and social interactions of patients, especially those of Asian descent, due to increased susceptibility to scarring and hyperpigmentation.
- Many Asia-Pacific countries lack comprehensive guidelines for acne management, contributing to suboptimal care, and existing guidelines often do not get updated regularly.
- The article emphasizes the need for better understanding and management of acne treatments, highlighting the efficacy of topical retinoids, particularly trifarotene, which has shown promise in reducing acne scars.