Publications by authors named "R K Chandyo"
Objective: Different definitions of thyroid dysfunction during pregnancy may lead to under or overtreatment. The aims of this study were to (1) define population-based pregnancy-specific reference ranges for thyroid dysfunction during early pregnancy in Nepal and assess the impact of antibody positivity, (2) quantify the diagnostic impact of population-based reference ranges compared with current practice and (3) assess the determinants of thyroid function and antibody positivity.
Methods: A total of 800 healthy pregnant women aged 20-40 years in the Bhaktapur municipality were included.
Background: The Ages and Stages Questionnaire 3rd edition (ASQ-3) could be a feasible tool in resource-poor settings. Little is known on the relationship between scores on the ASQ-3 and later intellectual abilities in these settings.
Aims: To examine the relationship between ASQ-3 scores during the first and second year of life and intellectual abilities at 4 years of age in Nepalese children.
Background: More than 90% of the morbidity and mortality from chronic respiratory disease occurs in low-income and middle-income countries (LMICs), with substantial economic impact. Preserved ratio impaired spirometry (PRISm) is a prevalent lung function abnormality associated with increased mortality in high-income countries. We aimed to conduct a post-hoc analysis of a cross-sectional study to assess the prevalence of, the risk factors for, and the impact of PRISm in three diverse LMIC settings.
View Article and Find Full Text PDFArticle Synopsis
- Brick kiln workers in Nepal are often overlooked and face high exposure to harmful silica, yet few use personal protective equipment (PPE) to safeguard their health.
- A study conducted in Bhaktapur revealed that only 28.9% of surveyed workers used respiratory PPE, with many lacking awareness about silicosis and the effectiveness of proper protective gear.
- Key factors influencing PPE use included higher household income and education levels, highlighting the need for improved education and resources to address knowledge gaps and encourage safety practices.
Article Synopsis
- - Brick kilns produce harmful emissions that negatively impact air quality and the health of nearby workers and residents, with limited evidence on the extent of these effects; a systematic review was conducted to analyze the pollution and its health consequences.
- - Out of 104 studies reviewed, the majority were from South Asia, focusing on key pollutants like particulate matter (PM), sulfur dioxide (SO), and carbon monoxide (CO), with common health issues including respiratory problems and musculoskeletal disorders among brick kiln workers.
- - The findings showed that traditional brick kilns emitted higher levels of PM and CO compared to improved designs, and while brick kiln workers generally had poorer health outcomes than unexposed individuals, the overall quality of the studies was low, indicating