Publications by authors named "R K Chakraverty"
Introduction: Graft-versus-host disease (GvHD) remains a major complication of allogeneic stem cell transplantation (allo-SCT), affecting 30-70% of patients (representing 800 new patients per year in the UK). The risk is higher in patients undergoing unrelated allo-SCT. About 1 in 10 patients die as a result of GvHD or through complications of its treatment.
View Article and Find Full Text PDFDevelopment of a conceptual framework for an electronic patient-reported outcome (ePRO) system measuring symptoms and impacts of CAR T-cell therapies in patients with haematological malignancies.
Lancet Oncol
October 2024
Article Synopsis
- CAR T-cell therapy can cause serious side effects, highlighting the need to understand patient experiences and quality of life through patient-reported outcomes (PROs).
- A study identified 178 relevant symptoms and concepts from 44 articles, which were categorized into four key areas: symptom burden, treatment impact, tolerability, and health-related quality of life.
- A conceptual framework was developed to improve the collection of PRO data, ensuring that patient perspectives are considered in managing treatment for those with blood cancers undergoing CAR T-cell therapy.
The application of antibiotics in the poultry and veterinary sectors is very common practice in India. Owing to the seriousness of antimicrobial resistance (AMR), the present study has illustrated the overall scenario of AMR in the poultry and veterinary sectors in India through an in-depth scoping review and key informant interview (KII). In the poultry sector, most of the studies reviewed have reported resistant bacteria isolated from chicken meat, eggs, cloacal swabs, and fecal samples, and only a few have reported the presence of resistant bacteria in and around the environment of poultry farms.
View Article and Find Full Text PDFBackground: Cardiovascular preventive strategies are guided by risk scores with unknown validity in cancer cohorts.
Objectives: This study aimed to evaluate the predictive performance of 7 established cardiovascular risk scores in cancer survivors from the UK Biobank.
Methods: The predictive performance of QRISK3, Systematic Coronary Risk Evaluation 2 (SCORE2)/Systematic Coronary Risk Evaluation for Older Persons (SCORE-OP), Framingham Risk Score, Pooled Cohort equations to Prevent Heart Failure (PCP-HF), CHARGE-AF, QStroke, and CHADS-VASc was calculated in participants with and without a history of cancer.