Biomarkers.

Background: Older adults with epilepsy represent the largest and fastest-growing segment of individuals with epilepsy and harbor risk factors for pathological aging, including cerebrovascular risk factors (CVRFs) and Alzheimer's disease (AD)-related pathology. In fact, several community-based studies have reported up to a 3-fold increased risk for dementia including AD among individuals with epilepsy. Despite this, identification of risk factors for AD and related dementias (ADRD) remains largely unexplored in epilepsy, which has critical implications for patient care and dementia risk stratification.

Dementia Care Practice.

Background: Stratifying risk of cognitive decline for an individual patient can be difficult in primary care settings where advanced biomarkers are usually not available. Passive risk calculators that capitalize on existing information contained in the electronic medical record (EMR) hold promise, but most are developed using EMR documentation of cognitive decline which is highly unreliable. This prospective study used objective cognitive testing to build a multivariable cognitive risk model based on EMR records.

Technology and Dementia Preconference.

Background: Stratifying risk of cognitive decline for an individual patient can be difficult in primary care settings where advanced biomarkers are usually not available. Passive risk calculators that capitalize on existing information contained in the electronic medical record (EMR) hold promise, but most are developed using EMR documentation of cognitive decline which is highly unreliable. This prospective study used objective cognitive testing to build a multivariable cognitive risk model based on EMR records.

Technology and Dementia Preconference.

Background: Test-retest reliability for existing cognitive screening tests is typically poor and most have ceiling effects and restricted score ranges that mask the presence of subtle decline. The Brief Assessment of Cognitive Health (BACH) is a computerized cognitive screening tool that patients complete independently. It includes a complex memory test without ceiling effects and brief mood and history questions.

Analysis of practical judgment in older adults with epilepsy: An exploratory, multicenter cohort study.

Despite the high prevalence of cognitive deficits in older people with epilepsy (PWE), their ability to judge and make decisions in daily life remains unexplored. In 61 older PWE (55-90 years) from the multicenter BRain Aging and Cognition in Epilepsy (BrACE) study, we examined everyday judgment, as measured by the Test of Practical Judgment (TOP-J: 9 questions, score range = 0-27; higher score = better judgment) and evaluated its association with clinical and demographic characteristics, global cognition, neuropsychological performance, subjective cognition, and quality of life (QOL). In our participants (mean age ± standard deviation [SD] = 66.