Publications by authors named "R K Aloor"
Article Synopsis
- Microscopic polyangiitis (MPA) is a type of autoimmune disease affecting small to medium blood vessels, primarily impacting the kidneys and lungs, with ANCA present in most cases, but some can be ANCA-negative needing biopsy for diagnosis.
- A 23-year-old man faced delayed diagnosis due to an unusual presentation of symptoms, showing negative ANCA and positive ANA, requiring a lung biopsy to confirm MPA after persistent symptoms.
- This case highlights the need to consider autoimmune vasculitis despite negative ANCA tests and the serious consequences of delayed diagnosis and treatment on patient health.
The mode of action of nuclear factor-κB (NF-κB) has been extensively observed in different aspects of cell growth and proliferation. The transcription factor regulates various genes controlling inflammation and anti-inflammatory responses in different tissues. Thus, NF-κB signal gains a therapeutic prospect.
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