Impact of periodontal therapy on general health: evidence from insurance data for five systemic conditions.

Background: Treatment of periodontal (gum) disease may lessen the adverse consequences of some chronic systemic conditions.

Purpose: To estimate the effects of periodontal therapy on medical costs and hospitalizations among individuals with diagnosed type 2 diabetes (T2D); coronary artery disease (CAD); cerebral vascular disease (CVD); rheumatoid arthritis (RA); and pregnancy in a retrospective observational cohort study.

Methods: Insurance claims data from 338,891 individuals with both medical and dental insurance coverage were analyzed in 2011-2013.

Association of a common genetic factor, PTGER3, with outcome of periodontal therapy and preterm birth.

Background: Clinical evidence suggests an association between preterm birth and periodontal disease. This study explores whether specific genetic polymorphisms are associated with success of periodontal therapy in pregnant women with periodontal disease and, further, whether any of these same polymorphisms are also associated with spontaneous preterm birth (sPTB).

Methods: One hundred sixty high-risk pregnant women (6 to 20 weeks of gestation) with periodontal disease (≥ 3 sites with attachment loss ≥ 4 mm) were studied.

Disposition and metabolism of N,N-dimethylacetoacetamide in male F344 and Wistar-Han rats and female B6C3F1 mice.

N,N-dimethylacetoacetamide (DMAAm) is a β-dicarbonyl compound used as an industrial intermediate. This study investigated the disposition and metabolism of [¹⁴C]DMAAm in male rats and female mice. A single oral dose of [¹⁴C]DMAAm (target dose of 10 or 130 mg/kg) was administered to male F344 and Wistar-Han rats.

Comparative methodologies for measuring metabolizable energy of various types of resistant high amylose corn starch.

Energy values of high amylose corn starches high in resistant starch (RS) were determined in vivo by two different methodologies. In one study, energy values were determined according to growth relative to glucose-based diets in rats fed diets containing RS(2), heat-treated RS(2) (RS(2)-HT), RS(3), and amylase predigested versions to isolate the RS component. Net metabolizable energy values ranged from 2.

A meta-analytic approach to determine the state of the science on implant dentistry.

Meta-analyses have been widely used to estimate treatment effects in evidence-based dentistry. Few conferences, however, have used a systems approach to assure coherent data management and analysis. The purpose of this section is to describe the data management and statistical analysis for the State of the Science of Implant Dentistry (SSID) conference.