Publications by authors named "R Jean"
Article Synopsis
- One third of organ donors experience catastrophic brain injury (CBI), but there’s no standardized management for traumatic CBI among trauma centers, leading to variability in practices.
- A multicenter trial involving 33 trauma centers analyzed 790 CBI patients to investigate whether institutions with CBI guidelines had higher organ donation rates.
- While centers with CBI guidelines showed greater use of certain treatments, the presence of guidelines did not significantly increase organ donation rates; however, hormone therapies were linked to a higher likelihood of donation.
Article Synopsis
- The study investigates how social vulnerability within a community impacts outcomes for patients involved in motor vehicle collisions (MVCs), focusing on the relationship between a patient’s home environment and the crash location.
- Researchers used crash data from Michigan and a social vulnerability index (SVI) to categorize areas by vulnerability levels, analyzing the interaction between home and crash environments.
- Results indicated that most MVCs occurred in areas with moderate social vulnerability, and while higher home SVI was associated with increased mortality odds initially, this significance diminished when vehicular and environmental factors were included in the analysis.
Introduction: Follicular Lymphoma (FL) results from the malignant transformation of germinal center (GC) B cells. FL B cells display recurrent and diverse genetic alterations, some of them favoring their direct interaction with their cell microenvironment, including follicular helper T cells (Tfh). Although FL-Tfh key role is well-documented, the impact of their regulatory counterpart, the follicular regulatory T cell (Tfr) compartment, is still sparse.
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