Saponins from Pea Ingredients to Innovative Sponge Cakes and Their Association with Perceived Bitterness.

Pea-based ingredients are increasingly being used in foods because of their nutritional, functional and environmental benefits. However, their bitter taste is not appreciated by consumers. Saponins have been reported to be bitter in whole pea flour (PF) but not in the purified ingredients obtained from it, such as pea protein isolate (PPI) and pea starch (PS).

digestion of protein and starch in sponge cakes formulated with pea ( L.) ingredients.

This study investigated the digestion of purified pea fractions (protein isolate and starch) in sponge cakes when compared to unrefined pea flour and to the whole wheat flour and purified maize starch commonly used in the food industry. Proteins in the wheat cake were hydrolysed more rapidly than those in cakes made with either pea flour or a combination of pea proteins and purified starch. In absolute terms, however, more readily bioaccessible protein was released from these pea cakes (by around 40%).

Towards Enhancing the Potential of Injection Molding Tools through Optimized Close-Contour Cooling and Additive Manufacturing.

This work deals with the parametric optimization of the position and form of a conformal cooling used in the injection molding industry. Based on a literature survey, an optimization routine concerning the parameter optimization of cooling system designs was developed and implemented with the help of the software package Moldflow. The main objective of the optimization is to reduce the cooling time; the second is to obtain an optimized homogeneous temperature distribution over the complete tool surface.

Functional PAK-2 knockout and replacement with a caspase cleavage-deficient mutant in mice reveals differential requirements of full-length PAK-2 and caspase-activated PAK-2p34.

p21-Activated protein kinase 2 (PAK-2) has both anti- and pro-apoptotic functions depending on its mechanism of activation. Activation of full-length PAK-2 by the monomeric GTPases Cdc42 or Rac stimulates cell survival, whereas caspase activation of PAK-2 to the PAK-2p34 fragment is involved in the apoptotic response. In this study we use functional knockout of PAK-2 and gene replacement with the caspase cleavage-deficient PAK-2D212N mutant to differentiate the biological functions of full-length PAK-2 and caspase-activated PAK-2p34.