Publications by authors named "R Jacubovich"

Background: Dichloromethane poisoning affects predominantly the central nervous and the cardiovascular systems, and results from both carboxyhemoglobin formation and direct solvent-related narcosis. Exposure is frequently occupational and related to paint-stripping. Several reports have described severe adverse effects as well as fatalities.

View Article and Find Full Text PDF

Background: The findings of the few epidemiological studies on the possible association between shortwave diathermy use by pregnant physiotherapists and adverse pregnancy outcome are inconsistent. We investigated such an association among physiotherapists in Israel.

Methods: Individualized data on exposure to shortwaves, ultrasound, and heavy lifting were collected by questionnaires and telephone interviews.

View Article and Find Full Text PDF

Thirty-two patients with high risk melanoma (either primary melanoma of the limbs or trunk, or recurrent melanoma) and clinically disease-free following appropriate surgical treatment were immunized with a vaccinia virus oncolysate made from a pool of 4 human melanoma cell lines. Injections were given id weekly for 3 months, and then bi-monthly for a further 21 months or until relapse. Treated patients have been under study for 11-72 months, and 15 of them for more than 36 months.

View Article and Find Full Text PDF

Ten human melanoma cell lines (HMCL) were tested for their ability to grow subcutaneously in nude mice. Using a standard inoculum, the HMCL could be characterized by their highly, fairly or poorly xenografting phenotype. These phenotypes were stable and the phenotype of one HMCL was recovered within cell clones derived from it.

View Article and Find Full Text PDF