Publications by authors named "R J van den Bosch"
Article Synopsis
- PTHrP and RBP4 are linked to worse kidney disease outcomes, and their relationship with PPARγ, a protective nuclear receptor, was investigated.
- The study examined levels of these proteins in different mouse models, including controls, diabetics, and those overexpressing PTHrP.
- Findings indicated that RBP4 and PTHrP levels increase during kidney pathology, suggesting that insulin and PPARγ play crucial roles in regulating their expression to maintain kidney health.
The persistence of HIV-1 proviruses in latently infected cells allows viremia to resume upon treatment cessation. To characterize the resulting immune response, we compare plasma proteomics and single-cell transcriptomics of peripheral blood mononuclear cells (PBMCs) before, during, and after detectable plasma viremia. We observe unique transcriptional signatures prior to viral rebound including a significant increase in CD16 monocytes with increased anti-viral gene expression.
View Article and Find Full Text PDFBiodegradable plastics, primarily aliphatic polyesters, degrade to varying extents in different environments. However, the absence of easily implementable techniques for screening microbial biodegradation potential -coupled with the limitations of non-functional omics analyses- has restricted comparative studies across diverse polymer types and ecosystems. In this study, we optimized a novel airbrushing method that facilitates functional analyses by simplifying the preparation of polyester-coated plates for biodegradation screening.
View Article and Find Full Text PDFObjectives: The present study performed a systematic review of the scientific literature that deals with the academic performance of university students with ADHD, collecting the research conducted between 2018 and 2024. Likewise, we aimed to know the factors that influence on academic performance and evaluate the tools used in the collection of ADHD symptoms and educational data.
Methods: The electronic databases PubMed, PsycInfo, and Scopus were used to search studies using PRISMA guidelines.
Article Synopsis
- * Germany has taken a leading role in implementing telemedicine for CHF, resulting in improved patient quality of life and fewer hospitalizations, supported by governmental backing and substantial research evidence.
- * This review analyzes the evolution of telemonitoring for CHF in Germany, highlighting key studies and the journey towards integrating telemedicine into standard care for high-risk patients.