Publications by authors named "R J Woodfield"
Article Synopsis
- The study investigated the accuracy of stroke identification methods in the UK Biobank, using genetic data to validate coding systems.
- The researchers created 12 different stroke definitions based on various medical codes and self-reports, analyzing data from over 408,000 participants.
- Results showed significant genetic correlations across all definitions compared to the MEGASTROKE study, highlighting variability in stroke case numbers related to coding sources while confirming some known genetic loci associated with stroke.
Objective: In UK Biobank (UKB), a large population-based prospective study, cases of many diseases are ascertained through linkage to routinely collected, coded national health datasets. We assessed the accuracy of these for identifying incident strokes.
Methods: In a regional UKB subpopulation (n = 17,249), we identified all participants with ≥1 code signifying a first stroke after recruitment (incident stroke-coded cases) in linked hospital admission, primary care, or death record data.
Background: Motor neurone disease (MND) is a rare neurodegenerative condition, with poorly understood aetiology. Large, population-based, prospective cohorts will enable powerful studies of the determinants of MND, provided identification of disease cases is sufficiently accurate. Follow-up in many such studies relies on linkage to routinely-collected health datasets.
View Article and Find Full Text PDFMalignant bone disease can cause significant morbidity. Monthly zoledronic acid (ZOL) reduces skeletal complications; however, limited data are available regarding long-term safety. We aimed to assess efficacy and safety of ZOL beyond 1 year of treatment.
View Article and Find Full Text PDFPurpose The purpose of this paper is to investigate the moderating role of psychopathy facets on the relationship between traumatic exposure and posttraumatic stress disorder (PTSD) symptomology. Design/methodology/approach Participants were male prisoners incarcerated in the UK. Findings The analysis revealed differential associations between the two facets of psychopathy, with potentially traumatic events and symptoms of PTSD.
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