Publications by authors named "R J Vaidya"
We present a case involving a 36-year-old male who experienced a nail gun injury to the posterolateral knee, leading to intraoperative nail removal. We observed bisection of the common peroneal nerve during the procedure with tethering, fortunately without any functional or sensory deficits.
View Article and Find Full Text PDFThyroglossal duct cysts (TGDCs) are typically located in the midline of the neck. Carcinomas arising within these cysts are extremely rare, with papillary carcinoma being the most common type. Diagnosis is generally confirmed postoperatively following excision.
View Article and Find Full Text PDFIntroduction: Intramedullary femoral nails (IMFNs) need to be removed for subsequent joint replacement, refracture, nonunion, or infection. The tools used to extract newer IMFNs may not be suited for removal of older implants, especially if broken. The purpose of this study was to describe a novel technique in femoral nail extraction when primary measures fail and a report on 6 cases where it was used.
View Article and Find Full Text PDFPolymeric nanoparticles (NPs) are traditionally formulated using batch methodologies that are poorly scalable and require time consuming, hands-on purification procedures. Here, we prepared poly(lactic acid) (PLA)-based polymeric NPs using a scalable microfluidics-based method and systematically investigated the impact of purification method (centrifugation tangential flow filtration (TFF)) to remove poly(vinyl alcohol) (PVA) on macrophage uptake, anti-inflammatory effects, biodistribution, and protein corona formation. TFF purification demonstrated significantly higher recovery of NPs compared to the centrifugation method, with little-to-no aggregation observed.
View Article and Find Full Text PDFArticle Synopsis
- Neighborhood socioeconomic deprivation (NSD) negatively affects reported outcomes in breast cancer patients, especially in terms of pain and overall wellbeing.
- A study analyzed data from 761 women in cancer symptom management trials, finding that those from more deprived neighborhoods reported worse physical and functional wellbeing (FWB) and higher pain.
- There’s a need for clinical trials to address community-level challenges faced by these patients, as interventions targeting these needs could help reduce health disparities.