Publications by authors named "R J Seward"

Article Synopsis
  • The study aimed to replicate the Step it UP! Game interventions for adults with disabilities by organizing participants into two competing teams, rewarding the team with the highest step count.
  • Experiment 1 tested an extended version of the game with longer sessions and showed that participants increased their step counts significantly.
  • Experiment 2 assessed whether adding experimenter interaction would improve results, but found that while participants still took more steps, the added interaction did not enhance the game's effectiveness.
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Purpose: Ultrasound biofeedback therapy (UBT) is a relatively new type of technology-assisted speech-language therapy and has shown promise in remediating speech sound disorders. However, there is a current lack of understanding of the barriers and benefits that may influence the usage behavior and clinical decision making for the implementation of UBT from a clinician perspective. In this qualitative study, we explore the perspectives of speech-language pathologists (SLPs) who have used ultrasound biofeedback in programs of speech sound therapy using the unified theory of acceptance and use of technology (UTAUT) model.

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Engaging in regular physical activity has been shown to decrease the risk of health conditions such as diabetes, heart disease, and high blood pressure. Several studies have shown that physical activity is lower among individuals with neuro-atypical developmental and intellectual disabilities as compared to neurotypical individuals. The current study evaluated the effects of the Step it UP! Game on the mean number of steps taken per minute with adults with disabilities.

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Article Synopsis
  • * The study focused on how immune complexes formed by biotherapeutic antibodies and tumor necrosis factor (TNF) affect peptide presentation in dendritic cells, using mass spectrometry to analyze the resulting HLAII immunopeptidome.
  • * Results showed that around 12,000 unique HLAII-associated peptides were identified, with anti-TNF sequences contributing a small proportion, indicating a complex relationship between therapy-induced immune responses and the presentation of therapeutic peptides.
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Ultrasound biofeedback therapy (UBT), which incorporates real-time imaging of tongue articulation, has demonstrated generally positive speech remediation outcomes for individuals with residual speech sound disorder (RSSD). However, UBT requires high attentional demands and may therefore benefit from a simplified display of articulation targets that are easily interpretable and can be compared to real-time articulation. Identifying such targets requires automatic quantification and analysis of movement features relevant to accurate speech production.

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