Percutaneous fixation for the treatment of metastatic spinal disease provides effective symptom palliation with low rates of hardware failure.

Background: The incidence of survival from metastatic spinal disease (MSD) continues to rise. However, open surgery for MSD is associated with significant perioperative morbidity, while minimally invasive percutaneous pedicle screw fixation (MIPPSF) offers reduced tissue trauma, less blood loss, and a reduction in complications. Lytic bone disease plus perioperative radiation further increase risk for instrument failure, especially in long construct MIPPSF.

History of atopy confers improved outcomes in IDH mutant and wildtype lower grade gliomas.

Purpose: A history of atopy or allergy has been shown to be protective against the development of glioma, however the effect of atopy on patient outcomes, especially in conjunction with the survival benefit associated with IDH mutation, has not yet been investigated, and is the focus of the study we present here.

Methods: Low grade glioma (LGG) data from the TCGA was downloaded, along with IDH, TERT, 1p/19q and ATRX mutational status and genetic alterations. History of asthma, eczema, hay fever, animal, or food allergies, as documented in TCGA, was used to determine patient atopy status.

Three-dimensional endoscopy in sinus surgery.

Purpose Of Review: Surgical endoscopy revolutionized the management of disease in nearly every surgical field, including rhinology. Endoscopy offered several advantages for the surgical management of rhinologic disease. However, it had a distinct disadvantage compared to direct vision, namely loss of binocular vision.