Pemphigus vulgaris in pregnancy with favourable foetal prognosis.

Pemphigus vulgaris is an immunobullous disease affecting the skin and mucous membranes most commonly during the fifth and sixth decades of life. Its occurrence in pregnancy is rare. We now report two severe cases of the disorder presenting during pregnancy and discuss its potential effects on the foetus and its management in pregnancy.

Neurological and adrenal dysfunction in the adrenal insufficiency/alacrima/achalasia (3A) syndrome.

Review of 20 patients with glucocorticoid deficiency (three cases also with salt loss) associated with absent tear secretion (19 cases) and achalasia of the cardia (15 cases) revealed neurological abnormalities in 17 including hyper-reflexia, muscle weakness, dysarthria, and ataxia together with impaired intelligence and abnormal autonomic function, particularly postural hypotension. These findings indicate that significant neurological problems are common in this multisystem disorder.

A study of the sources of delay in the diagnosis and treatment of undescended testicle.

Undescended testicle is the term applied to a group of congenital conditions which by their nature should be detected at birth. A study of the identification and treatment of cases of undescended testicle in one health district was undertaken through examination of hospital records. Altogether, only one in five cases of undescended testicle had been detected at birth.