Publications by authors named "R J Rona"

Article Synopsis
  • * Out of 191 adult ARDS patients on VV ECMO, 69% successfully switched to PSV, which led to better respiratory mechanics, increased compliance, and lower pulmonary shunt fraction.
  • * The findings suggest that PSV during VV ECMO is not only possible but may improve patient outcomes, with 94% of those transitioned to PSV being weaned from ECMO and a high percentage being discharged alive from ICU.
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Cell-free hemoglobin (CFH) is used to detect hemolysis and was recently suggested to trigger acute lung injury. However, its role has not been elucidated in severe acute respiratory distress syndrome (ARDS) patients undergoing extracorporeal membrane oxygenation (ECMO). We investigated the association of carboxyhemoglobin (COHb) and haptoglobin-two indirect markers of hemolysis-with mortality in critically ill patients undergoing veno-venous ECMO (VV-ECMO) with adjusted and longitudinal models (primary aim).

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Article Synopsis
  • Lung problems in COVID-19 can cause serious issues, like kidney injury, especially in patients on mechanical ventilation.
  • In a study with 157 patients, nearly half developed acute kidney injury (AKI), with most having it persist over time.
  • Higher ventilation levels were linked to more severe kidney issues, suggesting that problems with blood flow might connect the lung and kidney problems in COVID-19 patients.
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Objective: To present characteristics, surgical variables, complications, and postoperative care in pediatric patients with craniofacial synostosis undergoing Le Fort III osteotomy.

Background: Craniofacial synostoses are a group of genetic syndromes that result in premature fusion of cranial and facial sutures, leading to craniofacial deformities and associated complications. Midface advancement through Le Fort III osteotomy is the most frequent surgical option for these conditions.

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