Meeting expectations: the pilot evaluation of the Solihull Approach Parenting Group.

We have developed a new parenting group based on National Institute for Health and Clinical Excellence guidelines for parenting groups for conduct disorder and the Solihull Approach, a multi-agency approach to improve the parent-child relationship and behaviour management. Our aims were to create a parenting group that was theoretically coherent, of proven effectiveness, time efficient, for universal through to more complex problems, for parents of children from birth to 18 years, accessible to parents with literacy difficulties, able to be run by community practitioners such as health visitors and school nurses, and supported by a cost-effective and uncomplicated staff training model. This article describes the development of the Solihull Approach Parenting Group and the results of its first large-scale pilot evaluation.

Enhanced long-term potentiation in the hippocampus of rats expressing mutant presenillin-1 is age related.

Electrophysiological recordings were made from Fischer rats engineered to express the human presenilin 1 gene carrying the M146V mutation. Extracellular recordings of field excitatory post-synaptic potential (EPSPs) were made to investigate EPSP properties, paired pulse responses, posttetanic potentiation, and long-term potentiation in the stratum radiatum and dentate gyrus of hippocampal slices maintained in vitro. Transgenic rats aged approximately 6 months showed no differences from their wild-type littermates in any of these properties.