Publications by authors named "R J Puy"

Article Synopsis
  • The global rise in obesity has led to the need for clear guidelines combining medical, endoscopic, and surgical methods for effective treatment.
  • An expert panel formed by IFSO-EC created evidence-based recommendations for treating adults with a BMI of 30 or higher, focusing on integrating lifestyle interventions and various weight loss techniques.
  • These guidelines emphasize a comprehensive approach to obesity management, recognizing it as a complex, chronic disease that requires understanding all therapeutic options available.
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The benefit of levothyroxine treatment of subclinical hypothyroidism (SCH) is subject to debate. This study compared treatment satisfaction between older adults with SCH using levothyroxine or placebo. We analyzed pooled individual participant data from two randomized, double-blind, placebo-controlled trials investigating the effects of levothyroxine treatment in older adults with SCH.

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Article Synopsis
  • Recent advancements like OpenAI's ChatGPT-4 are being explored for their potential use in bariatric surgery decision-making as obesity rates rise.
  • The study involved a survey of thirty bariatric surgeons who assessed ten patient scenarios, comparing their recommendations with those provided by ChatGPT-4.
  • Results showed that ChatGPT-4 aligned with expert opinions 30% of the time, highlighting inconsistencies and the necessity for human expertise in effective treatment decisions.
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Context: With age, the prevalence of subclinical hypothyroidism rises. However, incidence and determinants of spontaneous normalization remain largely unknown.

Objective: To investigate incidence and determinants of spontaneous normalization of TSH levels in older adults with subclinical hypothyroidism.

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Background: Many older persons use the thyroid hormone levothyroxine which is often continued for life. Scientifically, there is much uncertainty whether simple continuation is the optimal approach. First, the physical need for levothyroxine can decrease with age thereby posing a higher risk of overtreatment and adverse effects.

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