Yielding of a model glass former: An interpretation with an effective system of icosahedra.

We consider the yielding under simple shear of a binary Lennard-Jones glass former whose super-Arrhenius dynamics are correlated with the formation of icosahedral structures. We recast this glass former as an effective system of icosahedra [Pinney et al., J.

Structure in sheared supercooled liquids: Dynamical rearrangements of an effective system of icosahedra.

We consider a binary Lennard-Jones glassformer whose super-Arrhenius dynamics are correlated with the formation of particles organized into icosahedra under simple steady state shear. We recast this glassformer as an effective system of icosahedra [Pinney et al., J.

Recasting a model atomistic glassformer as a system of icosahedra.

We consider a binary Lennard-Jones glassformer whose super-Arrhenius dynamics are correlated with the formation of icosahedral structures. Upon cooling, these icosahedra organize into mesoclusters. We recast this glassformer as an effective system of icosahedra which we describe with a population dynamics model.

Investigation of Smith's quinolone killing mechanisms during the PAE of ciprofloxacin on Escherichia coli.

Quinolone antibacterials interact with the DNA-DNA gyrase complex, but subsequent events that lead to cell death are unresolved. Three distinct mechanisms of quinolone lethality have been identified by Smith and co-workers: Mechanism A, which requires RNA and protein synthesis and cell division for expression; Mechanism B, which remains active when these functions are precluded; and Mechanism C, which is active on non-dividing cells. Exposure to 4x MIC ciprofloxacin (Cip) in nutrient broth (NB) for 3 h reduced the viability of Escherichia coli AB1157 to 0.