Publications by authors named "R J Penny"

Responsive feeding practices are crucial for developing healthy eating behaviours in children. However, chaotic households and financial stress may disrupt these practices. This cross-sectional study aimed to characterise feeding practices among Australian parents experiencing financial hardship.

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Background: High-affinity radiohybrid PSMA-targeting radiopharmaceutical F-flotufolastat (F-rhPSMA-7.3) is newly approved for diagnostic imaging of prostate cancer. Here, we conduct a post hoc analysis of two phase 3 studies to quantify F-flotufolastat uptake in a range of normal organs.

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Article Synopsis
  • Dengue virus (DENV) is a serious global health issue that can cause severe disease affecting various organs, including the kidneys, where immune responses and cell death mechanisms like pyroptosis and necroptosis play key roles.
  • The study focused on analyzing kidney tissue from victims of DENV to identify specific markers related to different cell death pathways (necroptosis, pyroptosis, and autophagy) and to understand tissue changes resulting from the infection.
  • Results showed significant kidney damage, including glomerular congestion and acute injury, with varying expressions of markers for autophagy, pyroptosis, and necroptosis, indicating an intricate
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  • A study evaluated the reproducibility of F-flotufolastat PET/CT scans in both newly diagnosed and recurrent prostate cancer patients using masked image readings from three independent readers.
  • The results showed high interreader agreement, with over 95% for newly diagnosed patients and at least 75% for recurrent cases, despite some complexities in the statistical analysis.
  • Intrareader reliability, when readers re-evaluated a subset of images, was also strong, maintaining over 86% agreement across both patient groups, indicating that these scans can be interpreted consistently.
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Background: Design thinking is an iterative process that innovates solutions through a person-centric approach and is increasingly used across health contexts. The person-centric approach lends itself to working with groups with complex needs. One such group is families experiencing economic hardship, who are vulnerable to food insecurity and face challenges with child feeding.

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