Automated tuning of a ring-assisted MZI-based interleaver for Kerr frequency combs.

We demonstrate a compact ring-assisted Mach-Zehnder interferometer (RAMZI)-based silicon photonic interleaver with a 400 GHz free spectral range (FSR), featuring flat passbands exceeding a spectral range of 50 nm. Additionally, we introduce a novel, to the best of our knowledge, add-on structure and tuning method enabling automated compensation for fabrication imperfections, precise shaping of the RAMZI flat-top passbands, and alignment with Kerr comb lines. Experimental results have shown successful interleaving of eight channels of distributed-feedback (DFB) lasers as well as a 200 GHz Kerr comb, both achieving an extinction ratio of approximately 20 dB.

Evaluating Telehealth Diagnostic Accuracy in Oral and Maxillofacial Diseases: A Comparative Study.

This study evaluated the accuracy of diagnosing oral and maxillofacial diseases using telehealth. We recruited 100 patients from the Oral Health Centre of Western Australia. They were either new patients or existing patients with a condition not previously diagnosed.

Harnessing the TAF1 Acetyltransferase for Targeted Acetylation of the Tumor Suppressor p53.

Pharmacological reactivation of the tumor suppressor p53 remains a key challenge for the treatment of cancer. Acetylation Targeting Chimera (AceTAC), a novel technology is previously reported that hijacks lysine acetyltransferases p300/CBP to acetylate the p53Y220C mutant. However, p300/CBP are the only acetyltransferases harnessed for AceTAC development to date.

Polychlorinated dibenzo-dioxin/furan and polychlorinated biphenyl concentrations in the human milk of individuals living near municipal waste incinerators in the UK: Findings from the Breast milk, Environment, Early-life, and development (BEED) human biomonitoring study.

The objective of this study is to report recent PCDD/F and PCB human milk concentrations in the United Kingdom (UK) and relate these to two proxies for exposure to municipal waste incinerator (MWI) emissions. As part of the Breast milk, Environment, Early-life, and Development (BEED) study, primiparous individuals were recruited from within 20 km of English MWIs between 2013 and 2015 and asked to provide human milk samples. The samples were analysed for quantitative concentrations of 17 PCDD/F and 12 PCB congeners.