Implementing and evaluating shared decision-making before transcatheter aortic valve implantation with a dedicated pathway and questionnaire.

Aims: Transcatheter aortic valve implantation (TAVI) is an alternative to surgical aortic valve replacement for patients with aortic valve stenosis. The choice between TAVI, surgery, or a conservative approach should be based upon multiple factors including clinical considerations, technical feasibility, and informed patient preference. In this context, engaging patients in a shared decision-making (SDM) process becomes essential, but this practice is generally underused.

Hydrogels Associated with Photodynamic Therapy Have Antimicrobial Effect against : A Systematic Review.

() is a Gram-positive bacterium that causes infections ranging from mild superficial cases to more severe, potentially fatal conditions. Many photosensitisers used in photodynamic therapy are more effective against superficial infections due to limitations in treating deeper tissue infections. Recently, attention to this bacterium has increased due to the emergence of multidrug-resistant strains, which complicate antibiotic treatment.

[Analysis of Medical Referrals from Primary Health Centers to the Otorhinolaryngology Department at Sótero del Río Hospital].

Unlabelled: Medical consultations play a crucial role in the collaboration between health centers, particularly in primary care settings, when managing complex pathologies beyond their scope. Analyzing the characteristics of consultations and their prioritization is essential for enhancing referrals to higher complexity centers. This study aims to profile the consultations referred from the primary health care of the South East Metropolitan Health Service to the Otorhinolaryngology Service of the Sótero del Río Hospital, while also evaluating the concordance in their prioritization.

Notch4 regulatory T cells and SARS-CoV-2 viremia shape COVID19 survival outcome.

Background: Immune dysregulation and SARS-CoV-2 plasma viremia have been implicated in fatal COVID-19 disease. However, how these two factors interact to shape disease outcomes is unclear.

Methods: We carried out viral and immunological phenotyping on a prospective cohort of 280 patients with COVID-19 presenting to acute care hospitals in Boston, Massachusetts and Genoa, Italy between June 1, 2020 and February 8, 2022.