Commonly used biomarkers do not contribute to diagnosing irritable bowel syndrome.

Objective: The aim of this article was to examine the costs and effectiveness of standardized blood and fecal investigations in patients fulfilling the Rome criteria for irritable bowel syndrome (IBS).

Methods: We conducted a real-life cohort study in patients fulfilling the Rome III criteria for IBS without red flag signs or symptoms, in a center of excellence for IBS patients from 1 January 2015 till 1 January 2019. Standardized blood and fecal investigations [hemoglobin (Hb), thyroid-stimulating hormone (TSH), coeliac serology, and fecal calprotectin (FCP)] were performed during the first consultation.

Micturition is associated with phase III of the interdigestive migrating motor complex in man.

Objectives: In previous manometric studies, we observed that micturition was associated with phase III of the migrating motor complex. The present study aimed to objectify this possible relationship and to examine whether modulation of micturition frequency influences migrating motor complex phase III incidence.

Methods: In a retrospective study, ambulatory antroduodenal manometry and micturition data of 27 subjects were analyzed.

Clinical relevance of antroduodenal manometry.

Objective: To evaluate the outcome of antroduodenal manometry studies and their effect on the clinical treatment of patients.

Design: A retrospective review of clinical antroduodenal manometric studies performed between September 1990 and March 1997 (n = 109).

Setting: Tertiary referral centre.

Gastrointestinal motor mechanisms in hyperglycaemia induced delayed gastric emptying in type I diabetes mellitus.

Background: Hyperglycaemia delays gastric emptying, both in healthy controls and in patients with diabetes mellitus. The effect of hyperglycaemia on antroduodenal motility in diabetes has not yet been studied.

Aim: To investigate the gastrointestinal motor mechanisms involved in the hyperglycaemia induced retardation of gastric emptying in patients with type I diabetes mellitus and autonomic neuropathy.

Effects of oral erythromycin on fasting and postprandial antroduodenal motility in patients with type I diabetes, measured with an ambulatory manometric technique.

Objective: The aim of this double-blind crossover study was to evaluate the effects of oral erythromycin (250 mg t.i.d.