Publications by authors named "R J Hillier"

Article Synopsis
  • The study aimed to find out what factors can predict how well a person's vision will be after surgery for a specific type of eye problem called rhegmatogenous retinal detachment.
  • Researchers tested patients' vision, focusing on problems like seeing things distorted (metamorphopsia) and differences in image size between both eyes (aniseikonia) three months after their surgery.
  • They found that damage to certain parts of the retina seen in special eye images was linked to worse vision outcomes after the surgery.
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Purpose: To assess long-term redetachment rates of the Pneumatic Retinopexy versus Vitrectomy for the Management of Primary Rhegmatogenous Retinal Detachment Outcomes Randomized Trial (PIVOT).

Design: Randomized controlled trial.

Subjects: PIVOT trial participants.

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Article Synopsis
  • This study compares the primary reattachment rate (PARR) of two treatments, pneumatic retinopexy (PnR) and pars plana vitrectomy (PPV), for patients with a specific type of retinal detachment.
  • It included 162 patients, where PARR was shown to be similar: 88.2% for PnR and 90.9% for PPV, with PnR providing better visual acuity outcomes.
  • The findings suggest that PnR can be considered a suitable first-line treatment for select patients, as it yields similar reattachment rates while enhancing visual recovery.
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Importance: There are reported benefits from vitrectomy for diabetic macular edema (DME); however, data precede anti-vascular endothelial growth therapy (VEGF) therapy, supporting a need to assess the current role of vitrectomy.

Objective: To determine rates of recruitment and efficacy outcomes of vitrectomy plus internal limiting membrane (ILM) peeling adjunctive to treat-and-extend (T&E) anti-VEGF injections for diabetic macular edema (DME).

Design, Setting, And Participants: This was a single-masked, multicenter randomized clinical trial at 21 sites in the United Kingdom from June 2018 to January 2021, evaluating single eyes of treatment-naive patients with symptomatic vision loss from DME for less than 1 year.

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Article Synopsis
  • This study aimed to compare the effectiveness and outcomes of four different surgical techniques for treating large idiopathic full-thickness macular holes in the eye.
  • The researchers analyzed data from 129 eyes over a period ranging from January 2018 to October 2022, finding a general anatomical success rate of 81%, although the standard internal limiting membrane (ILM) peel technique had significantly lower success at 59%.
  • Results showed that the pedicle transposition technique not only led to better visual recovery (27 ETDRS letters gained) compared to the free flap technique (12 letters gained) but also resulted in superior restoration of eye microstructure at both 3 and 6 months post-surgery.
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