Applicability of a serodiagnostic line blot for idiopathic inflammatory myopathy: the muscle biopsy is not all.

Introduction: Differential diagnosis of rare idiopathic inflammatory myopathies (IIM) is mainly based on clinical aspects, muscle biopsy analysis, and auxiliary assays that determine myositis-specific and associated autoantibodies (MSA and MAA). While MSAs are considered specific for their respective IIM subclass, MAAs can be present in more than one subclass and in other conditions. This study compares results of a multispecific line blot assay with the final diagnosis of IIM patients based on clinical features and muscle biopsy to draw conclusions for the test's applicability in the diagnostic workflow.

[Clinical approach to the patient with obesity document by the Argentine Society of Medicine, the Uruguayan Society of Internal Medicine, and the International Forum of Internal Medicine].

Obesity is one of the non-communicable chronic diseases with the highest increase in recent decades in Latin America, affecting children, adolescents, and especially young adults. Forty percent of adults have a body mass index greater than 25 kg/m2. Numerous studies have demonstrated a relationship between obesity and cardiovascular diseases such as hypertension, coronary artery disease, heart failure, cardiac arrhythmias, diabetes, sleep apnea, and oncological diseases, among others.

Demographics, Utilization, Workflow, and Outcomes Based on Observational Data From the RSNA-ACR 3D Printing Registry.

Purpose: The aim of this study was to report data from the first 3 years of operation of the RSNA-ACR 3D Printing Registry.

Methods: Data from June 2020 to June 2023 were extracted, including demographics, indications, workflow, and user assessments. Clinical indications were stratified by 12 organ systems.

Dried blood drops on vertical surfaces.

The analysis of structures in dried droplets has made it possible to detect the presence and conformational state of macromolecules in relevant biofluids. Therefore, the implementation of novel drying strategies for pattern formation could facilitate the identification of biomarkers for the diagnosis of pathologies. We present an experimental study of patterns formed by evaporating water-diluted blood droplets on a vertical surface.