Open globe injuries in children: a retrospective analysis.

Purpose: To study the outcome of open globe injuries in patients aged <14 years and compare the results between patients who presented approximately 30 years ago and a recent series.

Methods: Between January 1970 and January 1993, 180 eyes of children who presented with an open globe injury were retrospectively analyzed. Patients were divided into two groups.

Adult-onset foveomacular pigment epithelial dystrophy: clinicopathologic correlation of three cases.

Purpose: The authors describe the clinicopathologic features of three patients with adult onset foveomacular pigment epithelial dystrophy (AOFPED).

Methods: The eyes of three patients were studied ophthalmoscopically and by fluorescein angiography, and obtained postmortem and studied by light and electron microscopy.

Results: Histopathologic study of the three patient's eyes disclosed central loss of the retinal pigment epithelium and photoreceptor cell layer with a moderate number of pigment-containing macrophages present in the subretinal space and outer retina.

Effects of the human immunodeficiency virus type 1 Rev protein on reporter gene and host T-cell gene expression.

The HIV-1 encoded regulatory Rev protein acts to selectively increase the cytoplasmic concentration of incompletely spliced viral mRNAs through interaction with the Rev responsive element (RRE). In addition, the Rev activation domain, believed to be a nuclear export sequence, has been shown to modulate the export of non-RRE containing RNAs (e.g.

Morphometric analysis of pars plana development in humans.

Background: Quantitative features of pars plana development in humans are not well characterized. Knowledge of the dimensions of this region is important for our understanding of the anatomy of infant eyes for the purposes of surgery. The purpose of this study was to provide a morphometric description of pars plana growth in relation to 1) postconceptional age and 2) axial length.