Publications by authors named "R J G Chalmers"

Background: Contact lens discomfort (CLD) is a common problem for CL wearers, and patients with CLD often have changes in meibomian gland function and structure. In a Phase 2 trial AZR-MD-001 0.5% (AZR) ophthalmic ointment improved meibomian gland dysfunction (MGD) in non-lens wearers.

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  • - The study addresses anxiety as a common yet often overlooked symptom in Parkinson’s disease, aiming to create a new scale specifically designed to measure the distinct experiences of anxiety in these patients.
  • - Using data from a survey of 254 individuals with Parkinson's and anxiety, researchers developed both a comprehensive (CAPS-54) and a shortened version (CAPS-24) of the anxiety scale, assessing their reliability and validity through various analyses.
  • - The results indicate that these new scales possess excellent reliability and validity, providing a valuable tool for both researchers and clinicians to better understand and assess anxiety in Parkinson’s disease, with a recommendation for further validation with separate samples.
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  • Ulnar collateral ligament (UCL) injuries in the thumb often occur due to sports-related hyper-abduction or falls, and distinguishing between partial and complete tears can be difficult, especially in emergencies.
  • A study was conducted reviewing patients who underwent ultrasound for suspected UCL injuries, finding that ultrasound had a 63% accuracy rate in confirming complete tears compared to surgical findings.
  • While ultrasound is helpful for diagnosing UCL injuries, it has a significant false-positive rate of 37%, suggesting the need for additional imaging techniques to enhance accuracy.
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  • Parrots are often kept in captivity, but their welfare is not as well-studied as other captive animals, prompting this research to identify important welfare issues affecting them.
  • The study involved experts who ranked 28 identified welfare issues based on severity, duration, and prevalence, leading to a consensus on the top concerns after surveys and workshops.
  • The main welfare issues identified include lack of owner knowledge, social isolation, inadequate housing, poor nutrition, and insufficient veterinary training, which are crucial for guiding future efforts in improving parrot welfare.
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