Publications by authors named "R J Condon"
Histone deacetylase inhibitor decreases hyperalgesia in a mouse model of alcohol withdrawal-induced hyperalgesia.
Alcohol Clin Exp Res (Hoboken)
March 2024
Article Synopsis
- Alcohol withdrawal-induced hyperalgesia (AWH) results in heightened pain sensitivity after stopping chronic alcohol use, which can worsen withdrawal symptoms and increase relapse risk.
- * In this study, researchers assessed pain sensitivity in mice undergoing alcohol withdrawal through two different models: chronic drinking in the dark (DID) and the Lieber-DeCarli liquid diet.
- * Administering a histone deacetylase inhibitor (SAHA) during ethanol withdrawal improved pain sensitivity in mice on the Lieber-DeCarli diet, indicating a potential treatment for AWH.
Article Synopsis
- - The study investigated how different types of therapy (active, passive, manual) for low back pain affected the need for more intensive medical interventions over a year, such as opioid prescriptions and hospital visits.
- - Results showed that most patients received active therapies, but those who also had passive treatments were more likely to need additional care later, with a significant increase in risk linked to specific passive interventions like mechanical traction.
- - The findings suggest that while passive therapies are common, they may lead to worse health outcomes compared to manual therapy, prompting physical therapists to be careful about using these methods for low back pain treatment.
Introduction: Military training is associated with a high incidence of knee pain. Conversion from a rearfoot to non-rearfoot strike during running is effective at reducing knee pain in research environments. The purpose of this report was to demonstrate run retraining as a clinical intervention for service members with knee pain.
View Article and Find Full Text PDFBackground: Physical therapy (PT) is frequently used for the management of low back pain (LBP) within the US Departments of Defense (DOD) and Veterans Affairs (VA). However, variations in PT practice patterns and use of ineffective interventions lower the quality and increase the cost of care. Although adherence to the clinical practice guidelines (CPGs) can improve the outcomes and cost-effectiveness of LBP care, PT CPG adherence remains below 50%.
View Article and Find Full Text PDFWe report the effectiveness of automated text messaging for active surveillance of asymptomatic close contacts of coronavirus disease (COVID-19) cases in the Cork/Kerry region of Ireland. In the first 7 weeks of the COVID-19 outbreak, 1,336 close contacts received 12,421 automated texts. Overall, 120 contacts (9.
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