Designing an intervention to improve cognitive evaluations in primary care.

Background: Early diagnosis is crucial to the optimal management of patients with cognitive impairment due to Alzheimer's disease (AD) or AD-related dementias. For some patients, early detection of cognitive impairment enables access to disease-modifying therapies. For all patients, it allows access to psychosocial supports.

Camera-on-tip endoscope for cardiovascular diagnostics and surgical guidance.

Cardiovascular imaging with camera-on-tip endoscopes has the potential to provide physiologically relevant data on the tissue state and device placement that can improve clinical outcomes. In this work, we review the unmet clinical need for image-based cardiovascular diagnostics and guidance for minimally invasive procedures. We present a 7 Fr camera-on-tip endoscope with fibre-coupled multispectral illumination that includes methods for imaging in a blood-filled field of view (FOV).

A Preliminary Analysis of a Prosocial Intervention to Support Teachers and Staff Implementing Behavioral Interventions in a Specialized School Setting.

Prosocial is a systems-level intervention framework that incorporates elements of acceptance and commitment therapy (ACT) with Ostrom's core design principles (CDPs) guiding effective organizations and collective action (Ostrom, 1990). We evaluated a Prosocial intervention to support teachers and staff in a specialized school. AB analysis supported improvements in group cohesion and values-behavior alignment during the intervention and pre-post analyses showed significant improvements in psychological flexibility and perceived stress of participants.

Geographic disparities impacting oral vaccine performance: Observations and future directions.

Oral vaccines have several advantages compared with parenteral administration: they can be relatively cheap to produce in high quantities, easier to administer, and induce intestinal mucosal immunity that can protect against infection. These characteristics have led to successful use of oral vaccines against rotavirus, polio, and cholera. Unfortunately, oral vaccines for all three diseases have demonstrated lower performance in the highest-burden settings where they are most needed.

Securing the Future: Strategies for Global Polio Vaccine Security Amid Eradication Efforts.

As we commemorate 50 years of the Expanded Programme on Immunization (EPI), the global mission to eradicate polio stands at a critical juncture. While remarkable progress has been made over the past decades, ensuring a steady supply of polio vaccines remains a significant challenge that could undermine these achievements. This manuscript aims to address the complexities of polio vaccine security within the context of the Immunization Agenda 2030 (IA2030) and the Global Polio Eradication Strategy 2022-2029, proposing actionable strategies to strengthen the vaccine supply.