Gene Silencing via Ingestion of Double-Stranded RNA in Wireworm of Species.

Wireworms are the most destructive soil insect pests affecting horticultural crops. The damage often renders them unsuitable for commercial purposes, resulting in substantial economic losses. RNA interference (RNAi) has been broadly used to inhibit gene functions to control insect populations.

Past and future effects of climate on the metapopulation dynamics of a Northeast Atlantic seabird across two centuries.

Forecasting population responses to rapidly changing marine ecosystems requires mechanistic models integrating complex demographic processes, fitted to long time series, across large spatial scales. We used a Bayesian metapopulation model fit to colony census data and climatic covariates spanning 1900-2100 for all Northeast Atlantic colonies of an exemplar seabird, the Northern gannet (Morus bassanus) to investigate metapopulation dynamics under two climate scenarios. Fecundity varied non-linearly with near-surface air temperature and recruitment was depressed by sea surface temperature.

Simulated effects of surgical corrections on bone-implant micromotion and implant stresses in paediatric proximal femoral osteotomy.

Background And Objective: Proximal femoral osteotomy (PFO) is a surgical intervention, typically performed on paediatric population, that aims to correct femoral deformities caused by different pathologies (e.g., slipped capital femoral epiphysis).

iDiabetes platform-enhanced phenotyping of patients with diabetes for precision diagnosis, prognosis and treatment: study protocol for a cluster-randomised controlled study in Tayside, Scotland.

Introduction And Aim: Diabetes is a global health emergency with increasing prevalence and diabetes-associated morbidity and mortality. One of the challenges in optimising diabetes care is translating research advances in this heterogeneous disease into clinical care. A potential solution is the introduction of precision medicine approaches into diabetes care.

A Ball Python Colour Morph Implicates MC1R in Melanophore-Xanthophore Distribution and Pattern Formation.

Reptiles showcase an extensive array of skin colours and patterns, yet little is known about the genetics of reptile colouration. Here, we investigate the genetic basis of the Clown colour morph found in captive-bred ball pythons (Python regius) to study skin pigmentation and patterning in snakes. We obtained samples by crowdsourcing shed skin from commercial breeders and hobbyists.