Publications by authors named "R J Armitage"
Guiding molecular assembly of peptides into rationally engineered nanostructures remains a major hurdle against the development of functional peptide-based nanomaterials. Various non-covalent interactions come into play to drive the formation and stabilization of these assemblies, of which electrostatic interactions are key. Here, the atomistic mechanisms by which electrostatic interactions contribute toward controlling self-assembly and lateral association of ultrashort β-sheet forming peptides are deciphered.
View Article and Find Full Text PDFIntroduction: An increasing number of UK residents are travelling overseas to access medical treatments, the negative health consequences of which are largely managed by NHS doctors.
Methods: This paper performs an ethical analysis, using the ethical framework of principlism, of the duties of NHS doctors in managing these negative health consequences of medical tourism overseas.
Findings: While the doctor's duty to respect patient autonomy contains a negative duty to not interfere with their choice to access medical treatment overseas, it also contains a positive duty to ensure this choice is informed.
On Lateness: The Ethics of Running Behind Schedule in General Practice.
J Eval Clin Pract
February 2025
Introduction: GPs, at least in the United Kingdom, often run behind schedule in their clinics. This lateness is an inherently ethical problem due to the negative consequences it generates.
Methods: The paper outlines these negative consequences, attempts to classify the major reasons for such lateness, explores the ethical status of each of these reasons, and offers suggestions for how the negative consequences might be managed.
Article Synopsis
- The paper discusses the potential benefits and ethical implications of large language models (LLMs) in healthcare, focusing on how they could enhance patient care and clinical outcomes.
- LLMs could improve the efficiency of administrative tasks and directly inform clinical decisions but also pose risks of patient harm, necessitating careful risk management.
- Ethical considerations, particularly around beneficence, autonomy, and justice, suggest that while LLMs can standardize care and reduce biases, patient consent and alternative options must be prioritized to ensure ethical deployment in medical practice.