Publications by authors named "R J A de Kinderen"
Article Synopsis
- Diagnosing epilepsy can be hard and stressful, which affects people's lives and uses a lot of healthcare resources.
- The study wanted to see how an improved way of diagnosing epilepsy changed costs and people's quality of life over one year.
- Results showed that costs for healthcare went down a lot after using the new method, and people's quality of life got better too!
Background: The objective of the ZMILE study was to compare the effectiveness of a multicomponent self-management intervention (MCI) with care as usual (CAU) in adult patients with epilepsy (PWE) over a six-month period.
Methods: Participants (PWE & relative) were randomized into intervention or CAU groups. Self-report questionnaires were used to measure disease-specific self-efficacy as the primary outcome measure and general self-efficacy, adherence, seizure severity, emotional functioning, quality of life, proactive coping, and side-effects of antiepileptic drugs (AED) as secondary outcome measures.
Article Synopsis
- The study investigates how well the EQ-5D-5L and QOLIE-31P measures correlate in assessing quality of life in epilepsy patients, aiming to create a mapping function to predict EQ-5D-5L values from QOLIE-31P scores for economic evaluations.
- The research involved analyzing data from two clinical trials with 509 patient participants, calculating correlations and effect sizes between the two quality of life instruments over baseline and a 12-month follow-up.
- Findings revealed significant (but limited) correlations, highlighting the EQ-5D-5L's poor responsiveness in epilepsy, suggesting a need for specific tools for this condition, and raising doubts about the effectiveness of the mapping function for economic evaluations.
Background: People with epilepsy need to monitor and manage their symptoms. They, as well as their relatives, have to deal with the psychological burden, reflected in a reduced quality of life. Support in self-management can be of importance.
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