Inhibition of cryoglobulin synthesis as a method of positive influence on spermogram indices (clinical observations).

Introduction: Cold-shock precipitating proteins - cryoglobulins damage various vessels and, depending on the localization of damages, may lead to functional disorders of various organs and body systems. Evidently, cryoglobulinemia may have a negative influence on the reproductive system's condition, thus, this process requires detailed study.

Material And Methods: Clinical examples, indicating connection between cryoglobulinemia and spermatogenesis impairment are presented in the article.

Original inhibition method of excessive synthesis of pro-inflammatory cytokine of tumour necrosis factor α.

Influence on pro- and anti-inflammatory cytokines of an ill person is an urgent aspect of treatment of many diseases. For inhibition of synthesis of a high level of pro-inflammatory cytokines, medications which are recombinant monoclonal antibodies, especially to tumour necrosis factor α (TNF-α), are used. However, these methods of treatment require further improvement by elaborating new approaches with a wider spectrum of influence on the immune system.

Reduction of hyperproduction of thyroid autoantibodies in patients without disturbance of the thyroid function: new patents.

Unlabelled: A new method of reduction of autoimmune process activity related to the thyroid in patients without signs of thyroiditis is presented in the article (patent of Ukraine No. 103742). New patents and inventions from different countries of the world related to the problem have been analysed.

[Experience and problems of the primary health care centers' specialists in the implementation of the integrated health system based on family medicine in Ukraine].

The experience of the primary health care' centers in Lviv, Mykolaiv, Kherson regions on the basis of family medicine, integrated medical space, modern governance mechanisms, market technology, promotion trasmural' approach, intersectoral coordination and collaboration and preventative health care population allows to get the maximum effectiveness of the provision of public health in relation to a particular administrative area with limited resources.

Correction of fertility disorders in patients with cryoglobulinemia.

Introduction: Cryoglobulinemia can be among the causes of sperm bad quality. But conventional examination algorithm for patients with idiopathic oligozoospermia makes no provision for cryoglobulin determination in blood serum.

Materials And Methods: We examined 55 patients with idiopathic spermatogenesis disorder.