Publications by authors named "R Ide"
Background: Adjuvant docetaxel plus S1 (DS) chemotherapy after gastrectomy with D2 lymph node dissection is the standard treatment for stage III gastric cancer in Japan; however, some patients are unable to receive adequate drug administration because of the deterioration of their conditions. This study aimed to investigate the correlation between tolerability for postoperative adjuvant DS chemotherapy and prognosis, and the factors affecting tolerability.
Methods: This retrospective study involved patients with stage III gastric cancer who underwent curative resection between 2018 and 2021 from a multicenter database.
Quantum information processors benefit from high clock frequencies to fully harness quantum advantages before they are lost to decoherence. All-optical systems offer unique benefits due to their inherent 100-THz carrier frequency, enabling the development of THz-clock frequency processors. However, the bandwidth of quantum light sources and measurement devices has been limited to the MHz range, with nonclassical state generation rates in the kHz range.
View Article and Find Full Text PDFSuperficially spreading cervical squamous cell carcinoma (SCC) is the superficial extension of SCC of the cervix into the uterine lumen, replacing the endometrium. Here, we report a case of superficially spreading cervical SCC manifesting as intrauterine mural nodules with restricted diffusion on magnetic resonance imaging (MRI). A 76-year-old woman with a history of conization presented with a pelvic mass.
View Article and Find Full Text PDFArticle Synopsis
- This study examined the expression of proteins crucial for uterine contractions, comparing tissue samples from 38 PAM patients and 10 controls during cesarean sections.
- Results showed reduced expression of several contraction-associated proteins in PAM tissues, suggesting that inflammation could hinder uterine contractions and contribute to uterine atony, prompting the need for further research on the underlying mechanisms.
Article Synopsis
- - Dersimelagon is a selective medication being tested for treating certain rare disorders like erythropoietic protoporphyria and systemic sclerosis, but it is heavily processed by the liver, raising concerns for patients with liver issues.
- - Two studies were conducted to assess how liver and kidney impairments affect the drug's pharmacokinetics, which involves how the drug is absorbed and metabolized in the body.
- - Results showed that while mild liver impairment had similar effects on the drug, moderate impairment increased its concentration in the bloodstream significantly, and renal impairment also affected drug levels, though Dersimelagon was generally well tolerated among participants.